http://purl.uniprot.org/citations/29343666 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/29343666 | http://www.w3.org/2000/01/rdf-schema#comment | "Mitochondrial ribosomal protein L32 (MrpL32) of Saccharomyces cerevisiae is homologous to the bacterial L32 ribosomal protein. MrpL32 carries an N-terminal mitochondrion-targeting sequence (MTS) and is about 60 amino acid residues longer at the C-terminus. Adding to its function as a leader sequence, the MTS of MrpL32 has been reported to regulate ribosome biogenesis through its processing by m-AAA protease. However, the function of the C-terminal extension (CE) remains totally unknown. Therefore, we constructed a series of C-terminally truncated mrpl32 (mrpl32ΔC) genes and expressed them in a Δmrpl32 mutant to examine their function. Interestingly, some MrpL32ΔC derivatives exhibited temperature-sensitive (ts) growth on medium with non-fermentable carbon sources. Furthermore, the CE domain of MrpL32, expressed separately from MrpL32ΔC, could rescue the ts phenotype of mutants by improving mitochondrial protein synthesis."xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.org/dc/terms/identifier | "doi:10.1266/ggs.17-00023"xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/author | "Kitakawa M."xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/author | "Woogeng I.N."xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/name | "Genes Genet Syst"xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/pages | "21-24"xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/title | "The C-terminal extension domain of Saccharomyces cerevisiae MrpL32, a homolog of ribosomal protein L32, functions in trans to support mitochondrial translation."xsd:string |
http://purl.uniprot.org/citations/29343666 | http://purl.uniprot.org/core/volume | "93"xsd:string |
http://purl.uniprot.org/citations/29343666 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29343666 |
http://purl.uniprot.org/citations/29343666 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29343666 |
http://purl.uniprot.org/uniprot/#_A0A8H4BTF4-mappedCitation-29343666 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29343666 |
http://purl.uniprot.org/uniprot/#_P25348-mappedCitation-29343666 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29343666 |
http://purl.uniprot.org/uniprot/A0A8H4BTF4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/29343666 |
http://purl.uniprot.org/uniprot/P25348 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/29343666 |