http://purl.uniprot.org/citations/29443965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/29443965 | http://www.w3.org/2000/01/rdf-schema#comment | "Cerebrovascular disease is the third most common cause of death in developed countries, but our understanding of the cells that compose the cerebral vasculature is limited. Here, using vascular single-cell transcriptomics, we provide molecular definitions for the principal types of blood vascular and vessel-associated cells in the adult mouse brain. We uncover the transcriptional basis of the gradual phenotypic change (zonation) along the arteriovenous axis and reveal unexpected cell type differences: a seamless continuum for endothelial cells versus a punctuated continuum for mural cells. We also provide insight into pericyte organotypicity and define a population of perivascular fibroblast-like cells that are present on all vessel types except capillaries. Our work illustrates the power of single-cell transcriptomics to decode the higher organizational principles of a tissue and may provide the initial chapter in a molecular encyclopaedia of the mammalian vasculature."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature25739"xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Sun Y."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Ando K."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "He L."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Betsholtz C."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Andrae J."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Mochizuki N."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Raschperger E."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Keller A."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Lendahl U."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Nahar K."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Lebouvier T."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Mae M.A."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Vanlandewijck M."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Gouveia L."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Lavina B."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Rasanen M."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Del Gaudio F."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/author | "Zarb Y."xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/pages | "475-480"xsd:string |
http://purl.uniprot.org/citations/29443965 | http://purl.uniprot.org/core/title | "A molecular atlas of cell types and zonation in the brain vasculature."xsd:string |