| http://purl.uniprot.org/citations/29448105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29448105 | http://www.w3.org/2000/01/rdf-schema#comment | "During the development of type 2 diabetes, endoplasmic reticulum (ER) stress leads to pancreatic β cell failure. CCAAT/enhancer-binding protein (C/EBP) β is highly induced by ER stress and AMP-activated protein kinase (AMPK) suppression in pancreatic β cells, and its accumulation reduces pancreatic β cell mass. We investigated the phosphorylation state of C/EBPβ under these conditions. Casein kinase 2 (CK2) was found to co-localize with C/EBPβ in MIN6 cells. It phosphorylated S222 of C/EBPβ, a previously unidentified phosphorylation site. We found that C/EBPβ is phosphorylated by CK2 under AMPK suppression and ER stress, which are important from the viewpoint of the worsening pathological condition of type 2 diabetes, such as decreased insulin secretion and apoptosis of pancreatic β cells."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2018.02.108"xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Inoue K."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Matsuura Y."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Suzuki E."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Kido Y."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Hatano N."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Kanno A."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Matsuda T."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Takai T."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Ogawa W."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Kimura-Koyanagi M."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/author | "Asahara S.I."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/pages | "451-456"xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/title | "Casein kinase 2 phosphorylates and stabilizes C/EBPbeta in pancreatic beta cells."xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://purl.uniprot.org/core/volume | "497"xsd:string |
| http://purl.uniprot.org/citations/29448105 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29448105 |
| http://purl.uniprot.org/citations/29448105 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29448105 |
| http://purl.uniprot.org/uniprot/#_P28033-mappedCitation-29448105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29448105 |
| http://purl.uniprot.org/uniprot/#_Q8BPF9-mappedCitation-29448105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29448105 |
| http://purl.uniprot.org/uniprot/#_O54833-mappedCitation-29448105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29448105 |
| http://purl.uniprot.org/uniprot/#_O70192-mappedCitation-29448105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29448105 |