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http://purl.uniprot.org/citations/29513033http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29513033http://www.w3.org/2000/01/rdf-schema#comment"

Aim

To explore the association between the determinant factors including HLA-DQB1*03, DRB1-*07, -*13 and high-risk HPV infection, the cervical squamous cell carcinoma (CSCC) pathogenesis among Chinese Uighur and Han population.

Materials & methods

HLA alleles were genotyped by PCR sequence-specific primers.

Results

HPV16 infection rate was significantly higher among the Uighurs and Hans with CSCC as compared with healthy controls, respectively. HLA-DQB1*03 significantly increased among Uighurs with CSCC, while HLA-DRB1*07 significantly increased among Hans with CSCC. Similar tendencies were observed for DQB1*03 with HPV16-positive Uighurs CSCC and DRB1*07 with HPV16-positive Hans CSCC.

Conclusion

This study suggests that HLA-DQB1*03 and DRB1*07 alleles may influence the immune response to HPV16 infection and increase the risk of CSCC among the Uighurs and Hans in China."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.org/dc/terms/identifier"doi:10.2217/fon-2018-0048"xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Li F."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Tao L."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Shen X.H."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Liu C.X."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Wang X.L."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Liang W.H."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Hu J.M."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Li J.F."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Zhang H.J."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Pan X.L."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Xie Y.F."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Qi C.H."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Qi L.W."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/author"Pang L.J."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/name"Future Oncol"xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/pages"2005-2011"xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/title"HLA-DQB1*03 and DRB1*07 alleles increase the risk of cervical cancer among Uighur and Han women in Xinjiang, China."xsd:string
http://purl.uniprot.org/citations/29513033http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/29513033http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29513033
http://purl.uniprot.org/citations/29513033http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/29513033
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-29513033http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29513033
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