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http://purl.uniprot.org/citations/29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29518377http://www.w3.org/2000/01/rdf-schema#comment"Terminal differentiation of an organ is the last step in development that enables the organism to survive in the outside world after birth. Terminal differentiation of the insect tracheae that ends with filling the tubular network with gas is not fully understood at the tissue level. Here, we demonstrate that yet unidentified valves at the end of the tracheal system of the fruit fly Drosophila melanogaster embryo are important elements allowing terminal differentiation of this organ. Formation of these valves depends on the function of the zona pellucida protein Trynity (Tyn). The tracheae of tyn mutant embryos that lack these structures do not fill with gas. Additionally, external material penetrates into the tracheal tubes indicating that the tyn spiracles are permanently open. We conclude that the tracheal endings have to be closed to ensure gas-filling. We speculate that according to physical models closing of the tubular tracheal network provokes initial increase of the internal hydrostatic pressure necessary for gas generation through cavitation when the pressure is subsequently decreased."xsd:string
http://purl.uniprot.org/citations/29518377http://purl.org/dc/terms/identifier"doi:10.1016/j.ydbio.2018.02.019"xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/author"Berger J."xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/author"Wang Y."xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/author"Moussian B."xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/name"Dev Biol"xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/pages"75-83"xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/title"Trynity models a tube valve in the Drosophila larval airway system."xsd:string
http://purl.uniprot.org/citations/29518377http://purl.uniprot.org/core/volume"437"xsd:string
http://purl.uniprot.org/citations/29518377http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29518377
http://purl.uniprot.org/citations/29518377http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4KET3-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4KF98-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4KFA2-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_E1JGZ4-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4K7U4-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4K835-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4K782-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4KG51-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A0A0B4KGM2-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A8JNI3-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_A1Z714-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377
http://purl.uniprot.org/uniprot/#_B7YZI9-mappedCitation-29518377http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29518377