| http://purl.uniprot.org/citations/29578633 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29578633 | http://www.w3.org/2000/01/rdf-schema#comment | "The intracellular adaptor protein Mint2 binds amyloid precursor protein (APP) and presenilin-1, which are both central constituents of the amyloidogenic pathway associated with Alzheimer's disease (AD). Additional interaction partners have also been suggested for Mint2; several of them are also pertinent to AD pathogenesis. However, no comparative mapping of the Mint2 protein-protein interaction network is available. Here we provide a systematic characterization of seven interaction partners and address their specificities towards the different binding domains of Mint2, which reveal domain-specific and -nonspecific interaction partners. Moreover, we show that the last two C-terminal amino acids of Mint2 are both important for the intramolecular interaction with the PDZ1 domain and for the stability of Mint2."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.org/dc/terms/identifier | "doi:10.1002/cbic.201800004"xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/author | "Stromgaard K."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/author | "Albertsen L."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/author | "Haugaard-Kedstrom L.M."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/author | "Bartling C.R.O."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/author | "Jensen T.M.T."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/name | "Chembiochem"xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://purl.uniprot.org/core/title | "Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease."xsd:string |
| http://purl.uniprot.org/citations/29578633 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29578633 |
| http://purl.uniprot.org/citations/29578633 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29578633 |
| http://purl.uniprot.org/uniprot/Q99767#attribution-8FEFD3B0D5E802EA671AD625006F4113 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/29578633 |