| http://purl.uniprot.org/citations/29714684 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29714684 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29714684 | http://www.w3.org/2000/01/rdf-schema#comment | "C. elegans SET-9 and SET-26 are highly homologous paralogs that share redundant functions in germline development, but SET-26 alone plays a key role in longevity and heat stress response. Whereas SET-26 is broadly expressed, SET-9 is only detectable in the germline, which likely accounts for their different biological roles. SET-9 and SET-26 bind to H3K4me3 with adjacent acetylation marks in vitro and in vivo. In the soma, SET-26 acts through DAF-16 to modulate longevity. In the germline, SET-9 and SET-26 restrict H3K4me3 domains around SET-9 and SET-26 binding sites, and regulate the expression of specific target genes, with critical consequence on germline development. SET-9 and SET-26 are highly conserved and our findings provide new insights into the functions of these H3K4me3 readers in germline development and longevity."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.34970"xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.34970"xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Lee S.S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Lee S.S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Wang M."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Wang M."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Wang W."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Wang W."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "An S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "An S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Chaturbedi A."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Chaturbedi A."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Santhi S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/author | "Santhi S."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/title | "SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/title | "SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity."xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/29714684 | http://purl.uniprot.org/core/volume | "7"xsd:string |