| http://purl.uniprot.org/citations/29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29736797 | http://www.w3.org/2000/01/rdf-schema#comment | "Sinonasal glomangiopericytoma (SN-GPC) is an uncommon mesenchymal tumor with myoid differentiation. Recently, mutations in exon 3 of the gene coding for β-catenin (CTNNB1) and its nuclear expression were discovered in SN-GPC. β-catenin protein is a key regulatory molecule of the canonical Wnt signaling pathway. The expression of β-catenin target proteins is not well characterized in SN-GPC. We examined three SN-GPCs by immunohistochemistry and CTNNB1 mutation analysis. All cases expressed nuclear β-catenin. We identified CTNNB1 exon 3 mutations in two analyzable cases. Lymphoid enhancer-binding factor 1 (LEF1), a protein downstream from β-catenin, was also expressed in all cases. Our results further characterized the activation of the Wnt signaling pathway caused by CTNNB1 exon 3 mutation and suggest the utility of LEF1 immunohistochemistry in the differential diagnosis of SN-GPC."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00428-018-2370-9"xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Ichihara S."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Nakamura S."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Suzuki Y."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Kawasaki T."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Shimoyama Y."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Yanai H."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Kitagawa S."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/author | "Nakaguro M."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/name | "Virchows Arch"xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/pages | "235-239"xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/title | "beta-catenin (CTNNB1) mutation and LEF1 expression in sinonasal glomangiopericytoma (sinonasal-type hemangiopericytoma)."xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://purl.uniprot.org/core/volume | "473"xsd:string |
| http://purl.uniprot.org/citations/29736797 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29736797 |
| http://purl.uniprot.org/citations/29736797 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29736797 |
| http://purl.uniprot.org/uniprot/#_B4DGU4-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B4DSW9-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B2ZRE2-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B2ZRG2-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B4DL06-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B4DZY5-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |
| http://purl.uniprot.org/uniprot/#_B5BU28-mappedCitation-29736797 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29736797 |