RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29777698http://www.w3.org/2000/01/rdf-schema#comment"SURF4, which is located in the Surfeit gene cluster, encodes for a conserved integral membrane protein containing multiple putative transmembrane regions. However, the physiological role of SURF4 has not been determined. We found that SURF4 demonstrated aberrant amplification and increased expression in the tumor tissues of several human cancer patients. Overexpression of SURF4 led to increased cell proliferation, migration, and maintenance of anchorage-independent growth. In addition, NIH3T3 cells overexpressing SURF4 induced tumor growth in the mice. Collectively, our findings demonstrate that SURF4 has the potential for inducing cellular transformation and cell migration in vitro and has oncogenic transformation ability in vivo."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2018.05.116"xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Kim J.H."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Kim J."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Lee D."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Shin D.H."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Kim J.Y."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Park S.M."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Kim C.D."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Lim D.S."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Hong C.M."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/author"Kwon S.M."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/pages"43-47"xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/title"SURF4 has oncogenic potential in NIH3T3 cells."xsd:string
http://purl.uniprot.org/citations/29777698http://purl.uniprot.org/core/volume"502"xsd:string
http://purl.uniprot.org/citations/29777698http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29777698
http://purl.uniprot.org/citations/29777698http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/29777698
http://purl.uniprot.org/uniprot/#_B7Z1G8-mappedCitation-29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29777698
http://purl.uniprot.org/uniprot/#_B7Z7A8-mappedCitation-29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29777698
http://purl.uniprot.org/uniprot/#_B7Z8F3-mappedCitation-29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29777698
http://purl.uniprot.org/uniprot/#_O15260-mappedCitation-29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29777698
http://purl.uniprot.org/uniprot/#_B7Z605-mappedCitation-29777698http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29777698