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http://purl.uniprot.org/citations/29789500http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29789500http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29789500http://www.w3.org/2000/01/rdf-schema#comment"Human metapneumovirus (hMPV), a leading cause of respiratory tract infections in infants, encodes a small hydrophobic (SH) protein of unknown function. Here we show that infection of plasmacytoid dendritic cells (pDCs) with a recombinant virus lacking SH expression (rhMPV-ΔSH) enhanced the secretion of type I interferons (IFNs), which required TLR7 and MyD88 expression. HMPV SH protein inhibited TLR7/MyD88/TRAF6 signaling leading to IFN gene transcription, identifying a novel mechanism by which paramyxovirus SH proteins modulate innate immune responses."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.org/dc/terms/identifier"doi:10.3390/v10060278"xsd:string
http://purl.uniprot.org/citations/29789500http://purl.org/dc/terms/identifier"doi:10.3390/v10060278"xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Bao X."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Bao X."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Kolli D."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Kolli D."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Casola A."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Casola A."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Esham D."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Esham D."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Velayutham T.S."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/author"Velayutham T.S."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/name"Viruses"xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/name"Viruses"xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/title"Human Metapneumovirus Small Hydrophobic Protein Inhibits Interferon Induction in Plasmacytoid Dendritic Cells."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/title"Human Metapneumovirus Small Hydrophobic Protein Inhibits Interferon Induction in Plasmacytoid Dendritic Cells."xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/29789500http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/29789500http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29789500
http://purl.uniprot.org/citations/29789500http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29789500