| http://purl.uniprot.org/citations/29794219 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29794219 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29794219 | http://www.w3.org/2000/01/rdf-schema#comment | "The precatalytic spliceosome (B complex) is preceded by the pre-B complex. Here we report the cryo-electron microscopy structures of the Saccharomyces cerevisiae pre-B and B complexes at average resolutions of 3.3 to 4.6 and 3.9 angstroms, respectively. In the pre-B complex, the duplex between the 5' splice site (5'SS) and U1 small nuclear RNA (snRNA) is recognized by Yhc1, Luc7, and the Sm ring. In the B complex, U1 small nuclear ribonucleoprotein is dissociated, the 5'-exon-5'SS sequences are translocated near U6 snRNA, and three B-specific proteins may orient the precursor messenger RNA. In both complexes, U6 snRNA is anchored to loop I of U5 snRNA, and the duplex between the branch point sequence and U2 snRNA is recognized by the SF3b complex. Structural analysis reveals the mechanism of assembly and activation for the yeast spliceosome."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.aau0325"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.aau0325"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Lei J."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Lei J."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Yan C."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Yan C."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Bai R."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Bai R."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Wan R."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/author | "Wan R."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/pages | "1423-1429"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/pages | "1423-1429"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/title | "Structures of the fully assembled Saccharomyces cerevisiae spliceosome before activation."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/title | "Structures of the fully assembled Saccharomyces cerevisiae spliceosome before activation."xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/volume | "360"xsd:string |
| http://purl.uniprot.org/citations/29794219 | http://purl.uniprot.org/core/volume | "360"xsd:string |