| http://purl.uniprot.org/citations/2981859 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2981859 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2981859 | http://www.w3.org/2000/01/rdf-schema#comment | "A new gene function involved in the expression of mitochondrial cytochrome b is described. E158 is a respiratory deficient strain of Saccharomyces cerevisiae with a recessive mutation in nuclear DNA. The block in mitochondrial respiration is a consequence of the mutant's inability to synthesize cytochrome b. This has been confirmed by analysis of the mitochondrial translation products in E158. Since the mutant has wild-type concentrations of mature cytochrome b mRNA, the absence of the cytochrome b protein cannot be due to a transcriptional or RNA-processing defect. The wild-type gene (CBP6) responsible for the observed phenotype has been cloned by transformation of E158 with a genomic library of yeast nuclear DNA. The cloned gene has been sequenced and shown to code for a basic protein with a molecular weight of 18,657. Both deletion and disruption of the CBP6 coding sequence in chromosomal DNA of wild-type yeast lead to respiratory deficiency with a concomitant loss of cytochrome b. Part of the CBP6 gene has been fused to the trpE gene on a high expression Escherichia coli vector. The hybrid protein encoded by the trpE/CBP6 fusion has been purified from E. coli and used as an antigen for antibody production. Antibodies to the hybrid protein cross-react with an 18-kDa protein present in yeast mitochondria."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)89622-3"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)89622-3"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/author | "Dieckmann C.L."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/author | "Dieckmann C.L."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/author | "Tzagoloff A."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/author | "Tzagoloff A."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/pages | "1513-1520"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/pages | "1513-1520"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/title | "Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/title | "Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b."xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/volume | "260"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://purl.uniprot.org/core/volume | "260"xsd:string |
| http://purl.uniprot.org/citations/2981859 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2981859 |
| http://purl.uniprot.org/citations/2981859 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2981859 |
| http://purl.uniprot.org/citations/2981859 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2981859 |
| http://purl.uniprot.org/citations/2981859 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2981859 |
| http://purl.uniprot.org/uniprot/P07253 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2981859 |
| http://purl.uniprot.org/uniprot/P07253#attribution-E73730CA40908A82233E3207C9F4BCEC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/2981859 |