| http://purl.uniprot.org/citations/29878134 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29878134 | http://www.w3.org/2000/01/rdf-schema#comment | "Immature neurons generated by the subpallial MGE tangentially migrate to the cortex where they become parvalbumin-expressing (PV+) and somatostatin (SST+) interneurons. Here, we show that the Sp9 transcription factor controls the development of MGE-derived cortical interneurons. SP9 is expressed in the MGE subventricular zone and in MGE-derived migrating interneurons. Sp9 null and conditional mutant mice have approximately 50% reduction of MGE-derived cortical interneurons, an ectopic aggregation of MGE-derived neurons in the embryonic ventral telencephalon, and an increased ratio of SST+/PV+ cortical interneurons. RNA-Seq and SP9 ChIP-Seq reveal that SP9 regulates MGE-derived cortical interneuron development through controlling the expression of key transcription factors Arx, Lhx6, Lhx8, Nkx2-1, and Zeb2 involved in interneuron development, as well as genes implicated in regulating interneuron migration Ackr3, Epha3, and St18. Thus, Sp9 has a central transcriptional role in MGE-derived cortical interneuron development."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.org/dc/terms/identifier | "doi:10.1093/cercor/bhy133"xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Chen B."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Li Z."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Liang Q."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Wang Y."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Wen Y."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "You Y."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Yang Z."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Wei S."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Xu Z."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Rubenstein J.L."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Tao G."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/author | "Lindtner S."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/name | "Cereb Cortex"xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/pages | "2653-2667"xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/title | "Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development."xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://purl.uniprot.org/core/volume | "29"xsd:string |
| http://purl.uniprot.org/citations/29878134 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29878134 |
| http://purl.uniprot.org/citations/29878134 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29878134 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXN3-mappedCitation-29878134 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/29878134 |