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http://purl.uniprot.org/citations/29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29886014http://www.w3.org/2000/01/rdf-schema#comment"One of the most critical steps of protein biosynthesis is the coupled movement of mRNA, which encodes genetic information, with tRNAs on the ribosome. In eukaryotes, this process is catalyzed by a conserved G-protein, the elongation factor 2 (eEF2), which carries a unique post-translational modification, called diphthamide, found in all eukaryotic species. Here we present near-atomic resolution cryo-electron microscopy structures of yeast 80S ribosome complexes containing mRNA, tRNA and eEF2 trapped in different GTP-hydrolysis states which provide further structural insights into the role of diphthamide in the mechanism of translation fidelity in eukaryotes."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.org/dc/terms/identifier"doi:10.1016/j.jmb.2018.06.006"xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Hashem Y."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Pellegrino S."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Mancera-Martinez E."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Melnikov S."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Yusupov M."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Yusupova G."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Simonetti A."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Myasnikov A."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/author"Demeshkina N."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/name"J Mol Biol"xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/pages"2677-2687"xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/title"Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance."xsd:string
http://purl.uniprot.org/citations/29886014http://purl.uniprot.org/core/volume"430"xsd:string
http://purl.uniprot.org/citations/29886014http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/29886014
http://purl.uniprot.org/citations/29886014http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/29886014
http://purl.uniprot.org/uniprot/#_P0C0V8-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014
http://purl.uniprot.org/uniprot/#_P0C0W1-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014
http://purl.uniprot.org/uniprot/#_P0C2H6-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014
http://purl.uniprot.org/uniprot/#_P0C2H8-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014
http://purl.uniprot.org/uniprot/#_P14120-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014
http://purl.uniprot.org/uniprot/#_P14126-mappedCitation-29886014http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/29886014