| http://purl.uniprot.org/citations/2990892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2990892 | http://www.w3.org/2000/01/rdf-schema#comment | "Yeast cytochrome c oxidase contains three large subunits made in mitochondria and at least six smaller subunits made in the cytoplasm. There is evidence that the catalytic centers (heme a and copper) are associated with the mitochondrially-made subunits, but the role of the cytoplasmically-made subunits has remained open. Using a gene interruption technique, we have now constructed a Saccharomyces cerevisiae mutant which lacks the largest of the cytoplasmically-made subunits (subunit IV). This mutant is devoid of cyanide-sensitive respiration, the absorption spectrum of cytochrome aa3 and cytochrome c oxidase activity. It still contains the other cytochrome c oxidase subunits but these are not assembled into a stable complex. Active cytochrome c oxidase was restored to the mutant by introducing a plasmid-borne wild-type subunit IV gene; no restoration was seen with a gene carrying an internal deletion corresponding to amino acid residues 28-66 of the mature subunit. Subunit IV is thus necessary for proper assembly of cytochrome c oxidase."xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1985.tb02334.x"xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/author | "Schatz G."xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/author | "Dowhan W."xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/author | "Bibus C.R."xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/pages | "179-184"xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/title | "The cytoplasmically-made subunit IV is necessary for assembly of cytochrome c oxidase in yeast."xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://purl.uniprot.org/core/volume | "4"xsd:string |
| http://purl.uniprot.org/citations/2990892 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2990892 |
| http://purl.uniprot.org/citations/2990892 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2990892 |
| http://purl.uniprot.org/uniprot/#_P04037-mappedCitation-2990892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/2990892 |
| http://purl.uniprot.org/uniprot/P04037 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/2990892 |