http://purl.uniprot.org/citations/30007418 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/30007418 | http://www.w3.org/2000/01/rdf-schema#comment | "Modern genetic approaches are powerful in providing access to diverse cell types in the brain and facilitating the study of their function. Here, we report a large set of driver and reporter transgenic mouse lines, including 23 new driver lines targeting a variety of cortical and subcortical cell populations and 26 new reporter lines expressing an array of molecular tools. In particular, we describe the TIGRE2.0 transgenic platform and introduce Cre-dependent reporter lines that enable optical physiology, optogenetics, and sparse labeling of genetically defined cell populations. TIGRE2.0 reporters broke the barrier in transgene expression level of single-copy targeted-insertion transgenesis in a wide range of neuronal types, along with additional advantage of a simplified breeding strategy compared to our first-generation TIGRE lines. These novel transgenic lines greatly expand the repertoire of high-precision genetic tools available to effectively identify, monitor, and manipulate distinct cell types in the mouse brain."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2018.06.035"xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Huang L."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Li L."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Gu H."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Walker M."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Smith K.A."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Yao Z."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Zeng H."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Nguyen T.N."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Mills M."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Larsen R.S."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Lin M.Z."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Murphy G.J."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Madisen L."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Larsen R."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Harris J.A."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Ting J.T."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Harrington J."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Baker C.A."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Tasic B."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Boyden E.S."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Sunkin S.M."xsd:string |
http://purl.uniprot.org/citations/30007418 | http://purl.uniprot.org/core/author | "Waters J."xsd:string |