DESCRIBE <http://purl.uniprot.org/citations/30058675>

Subject	Predicate	Object
http://purl.uniprot.org/citations/30058675	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/30058675	http://www.w3.org/2000/01/rdf-schema#comment	" Objective To detect the expressions of micro ribonucleic acid (miR)-129 and its target gene in uterine fibroid tissues and to investigate the role of miR-129 in the occurrence of uterine fibroid. Patients and methods The expressions of miR-129 and its target gene ten-eleven translocation 1 (TET1) were detected via quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Dual-luciferase reporter gene and Western blotting were used to verify the regulatory relation between miR-129 and target gene. The effects of miR-129 on the proliferation, apoptosis, cycle and extracellular matrix (ECM) of uterine fibroid cells were investigated via transfection with miR-129 mimics and TET1 small-interfering RNA (siRNA). Results MiR-129 was lowly expressed in uterine fibroid. The expression of miR-129 was regulated by sex hormones. The highly expressed miR-129 promoted apoptosis and inhibited proliferation through reducing the low expression of TET1. At the same time, miR-129 affected the accumulation of ECM. Conclusions The expression of miR-129 in uterine fibroid is lower, and the proliferation capacity of tumor cells is enhanced, thus promoting the occurrence and development of uterine fibroid."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.org/dc/terms/identifier	"doi:10.26355/eurrev_201807_15492"xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Lin L."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Zhao L."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Han S.C."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Liu H.X."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Yue C."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Lu J.L."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/author	"Bi J.L."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/date	"2018"xsd:gYear
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/name	"Eur Rev Med Pharmacol Sci"xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/pages	"4419-4426"xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/title	"MiR-129 is involved in the occurrence of uterine fibroid through inhibiting TET1."xsd:string
http://purl.uniprot.org/citations/30058675	http://purl.uniprot.org/core/volume	"22"xsd:string
http://purl.uniprot.org/citations/30058675	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/30058675
http://purl.uniprot.org/citations/30058675	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/30058675
http://purl.uniprot.org/uniprot/#_B3W6H5-mappedCitation-30058675	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/#_B3W6H6-mappedCitation-30058675	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/#_B3W6H8-mappedCitation-30058675	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/#_Q8NFU7-mappedCitation-30058675	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/Q8NFU7	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/B3W6H5	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/B3W6H8	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/30058675
http://purl.uniprot.org/uniprot/B3W6H6	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/30058675