| http://purl.uniprot.org/citations/30068950 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30068950 | http://www.w3.org/2000/01/rdf-schema#comment | "Flagellin is amongst the most abundant proteins in flagellated bacterial species and constitutes the major building block of the flagellar filament. The proteins FliW and FliS serve in the post-transcriptional control of flagellin and guide the protein to the flagellar type III secretion system (fT3SS), respectively. Here, we present the high-resolution structure of FliS/flagellin heterodimer and show that FliS and FliW bind to opposing interfaces located at the N- and C-termini of flagellin. The FliS/flagellin/FliW heterotrimer is able to interact with FlhA-C suggesting that FliW and FliS are released during flagellin export. After release, FliW and FliS are recycled to execute a new round of post-transcriptional regulation and targeting. Taken together, our study provides a mechanism explaining how FliW and FliS synchronize the production of flagellin with the capacity of the fT3SS to secrete flagellin."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41598-018-29884-8"xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Linne U."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Mukherjee S."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Altegoer F."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Bange G."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Kearns D.B."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Steinchen W."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/author | "Bedrunka P."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/pages | "11552"xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/title | "FliS/flagellin/FliW heterotrimer couples type III secretion and flagellin homeostasis."xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/30068950 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30068950 |
| http://purl.uniprot.org/citations/30068950 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30068950 |
| http://purl.uniprot.org/uniprot/#_P02968-mappedCitation-30068950 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30068950 |
| http://purl.uniprot.org/uniprot/#_P39739-mappedCitation-30068950 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30068950 |
| http://purl.uniprot.org/uniprot/P02968 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30068950 |
| http://purl.uniprot.org/uniprot/P39739 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30068950 |