http://purl.uniprot.org/citations/30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/30082278 | http://www.w3.org/2000/01/rdf-schema#comment | "The specification of tissue identity during embryonic development requires precise spatio-temporal coordination of gene expression. Many transcription factors required for the development of organs have been identified and their expression patterns are known; however, the mechanisms through which they coordinate gene expression in time remain poorly understood. Here, we show that hormone-induced transcription factor Blimp-1 participates in the temporal coordination of tubulogenesis in Drosophila melanogaster by regulating the expression of many genes involved in tube maturation. In particular, we demonstrate that Blimp-1 regulates the expression of genes involved in chitin deposition and F-actin organization. We show that Blimp-1 is involved in the temporal control of lumen maturation by regulating the beginning of chitin deposition. We also report that Blimp-1 represses a variety of genes involved in tracheal maturation. Finally, we reveal that the kinase Btk29A serves as a link between Blimp-1 transcriptional repression and apical extracellular matrix organization."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.118.301444"xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/author | "Casanova J."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/author | "Araujo S.J."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/author | "Stephan-Otto Attolini C."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/author | "Ozturk-Colak A."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/pages | "653-663"xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/title | "Blimp-1 Mediates Tracheal Lumen Maturation in Drosophila melanogaster."xsd:string |
http://purl.uniprot.org/citations/30082278 | http://purl.uniprot.org/core/volume | "210"xsd:string |
http://purl.uniprot.org/citations/30082278 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30082278 |
http://purl.uniprot.org/citations/30082278 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30082278 |
http://purl.uniprot.org/uniprot/#_M9PCD8-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_M9PBR0-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_Q9VUF8-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_M9PCX8-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_M9PI59-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_P08630-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/#_Q9VRN4-mappedCitation-30082278 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/Q9VUF8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/Q9VRN4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/M9PCX8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30082278 |
http://purl.uniprot.org/uniprot/M9PBR0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30082278 |