| http://purl.uniprot.org/citations/30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30098009 | http://www.w3.org/2000/01/rdf-schema#comment | "CIZ1 plays a role in DNA synthesis at the G1/S checkpoint. Ciz1 gene-trap null mice manifest motor dysfunction, cell-cycle abnormalities, and DNA damage. In contrast, it has previously been reported that mouse embryonic fibroblasts derived from presumed Ciz1 knock-out mice (Ciz1tm1.1Homy/tm1.1Homy ) generated by crossing Cre-expressing mice with exon 5-floxed mice (Ciz1tm1Homy/tm1Homy ) do not exhibit evidence of enhanced DNA damage following γ-irradiation or cell-cycle defects. Here, we report that Ciz1tm1.1Homy/tm1.1Homy mice show loss of Ciz1 exon 5 but are neurologically normal and express abnormal transcripts (Ciz1ΔE5/ΔE5 mice) that are translated into one or more proteins of approximate wild-type size. Therefore, Ciz1tm1.1Homy/tm1.1Homy mice (Ciz1ΔE5/ΔE5 ) lose residues encoded by exon 5 but may gain function from novel amino acid sequences."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.org/dc/terms/identifier | "doi:10.1002/1873-3468.13221"xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/author | "Tian J."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/author | "Xiao J."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/author | "Khan M.M."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/author | "LeDoux M.S."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/author | "Vemula S."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/pages | "3101-3110"xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/title | "Consequences of Cre-mediated deletion of Ciz1 exon 5 in mice."xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://purl.uniprot.org/core/volume | "592"xsd:string |
| http://purl.uniprot.org/citations/30098009 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30098009 |
| http://purl.uniprot.org/citations/30098009 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30098009 |
| http://purl.uniprot.org/uniprot/#_A0A0A0MQJ7-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVQ0-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_A2AN61-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_F6XWQ4-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_O35474-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
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| http://purl.uniprot.org/uniprot/#_F7BM53-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_F7D5G9-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_F6S5B6-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |
| http://purl.uniprot.org/uniprot/#_Q3TXU6-mappedCitation-30098009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30098009 |