| http://purl.uniprot.org/citations/3010294 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3010294 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3010294 | http://www.w3.org/2000/01/rdf-schema#comment | "The qa-1S gene, one of two regulatory genes in the qa gene cluster of Neurospora crassa, encodes the qa repressor. The qa-1S gene together with the qa-1F gene, which encodes the qa activator protein, control the expression of all seven qa genes, including those encoding the inducible enzymes responsible for the utilization of quinic acid as a carbon source. The nucleotide sequence of the qa-1S gene and its flanking regions has been determined. The deduced coding sequence for the qa-1S protein encodes 918 amino acids with a calculated molecular weight of 100,650 and is interrupted by a single 66-base-pair intervening sequence. Both constitutive and noninducible mutants occur in the qa-1S gene and two different mutations of each type have been cloned and sequenced. All four mutations occur within the predicted coding region of the qa-1S gene. This result strongly supports the hypothesis that the qa-1S gene encodes a repressor. All four mutations are located within codons for the last 300 amino acids of the qa-1S protein. The mutations in three of the mutants involve amino acid substitutions, while the fourth mutant, which has a constitutive phenotype, contains a frameshift mutation. The two constitutive mutations occur in the most distal region of the gene, possibly implicating the COOH-terminal region of the qa repressor in binding to its target. The two noninducible mutations occur in a region proximal to the constitutive mutations, possibly implicating this region of the qa repressor in binding the inducer."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.83.10.3381"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.83.10.3381"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/author | "Giles N.H."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/author | "Giles N.H."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/author | "Huiet L."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/author | "Huiet L."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/pages | "3381-3385"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/pages | "3381-3385"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/title | "The qa repressor gene of Neurospora crassa: wild-type and mutant nucleotide sequences."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/title | "The qa repressor gene of Neurospora crassa: wild-type and mutant nucleotide sequences."xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/volume | "83"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://purl.uniprot.org/core/volume | "83"xsd:string |
| http://purl.uniprot.org/citations/3010294 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3010294 |
| http://purl.uniprot.org/citations/3010294 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3010294 |
| http://purl.uniprot.org/citations/3010294 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3010294 |
| http://purl.uniprot.org/citations/3010294 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3010294 |
| http://purl.uniprot.org/uniprot/P11637 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3010294 |
| http://purl.uniprot.org/uniprot/Q01393 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3010294 |