| http://purl.uniprot.org/citations/30111845 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30111845 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30111845 | http://www.w3.org/2000/01/rdf-schema#comment | "Precursor-B cell acute lymphoblastic leukemia (pre-B ALL) is the most common pediatric cancer, but there are no useful zebrafish pre-B ALL models. We describe the first highly-penetrant zebrafish pre-B ALL, driven by human MYC. Leukemias express B lymphoblast-specific genes and are distinct from T cell ALL (T-ALL)-which these fish also develop. Zebrafish pre-B ALL shares in vivo features and expression profiles with human pre-B ALL, and these profiles differ from zebrafish T-ALL or normal B and T cells. These animals also exhibit aberrant lymphocyte development. As the only robust zebrafish pre-B ALL model and only example where T-ALL also develops, this model can reveal differences between MYC-driven pre-B vs. T-ALL and be exploited to discover novel pre-B ALL therapies."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41375-018-0226-6"xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Shah R."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Shah R."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Park G."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Park G."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Miles R.R."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Miles R.R."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Foster C."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Foster C."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Hasan A."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Hasan A."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Te Kronnie G."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Te Kronnie G."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Ahmed S.T."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Ahmed S.T."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Batchelor L."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Batchelor L."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Borga C."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Borga C."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Bresolin S."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Bresolin S."xsd:string |
| http://purl.uniprot.org/citations/30111845 | http://purl.uniprot.org/core/author | "Burroughs-Garcia J."xsd:string |