| http://purl.uniprot.org/citations/3019675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3019675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3019675 | http://www.w3.org/2000/01/rdf-schema#comment | "We have demonstrated the presence of an Epstein-Barr virus (EBV)-coded thymidine kinase (TK) by producing biochemically transformed, TK-positive mammalian cell lines using either microinjection of whole EBV virions or calcium phosphate-mediated transfection of the SalI-B restriction endonuclease fragment of EBV DNA. Analysis of these cell lines showed that: (i) EBV DNA was present in the cell lines, (ii) sequences from the SalI-B restriction endonuclease fragment of EBV were expressed, (iii) a TK activity was present and (iv) a protein with antigenic cross-reactivity with the herpes simplex virus (HSV) TK was produced. The identity of the EBV TK gene was determined by demonstrating that a recombinant plasmid, which expressed the protein product of the BXLF1 open reading frame as a fusion protein, could complement TK-strains of E. coli. A comparison of the predicted amino acid sequences of the TK proteins of EBV and HSV-1 revealed significant regions of homology."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1986.tb04450.x"xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1986.tb04450.x"xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Arrand J.R."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Arrand J.R."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Littler E."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Littler E."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "McBride A.A."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "McBride A.A."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Powell K.L."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Powell K.L."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Soerensen E.T."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Soerensen E.T."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Walsh-Arrand J.E."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Walsh-Arrand J.E."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Zeuthen J."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/author | "Zeuthen J."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/pages | "1959-1966"xsd:string |
| http://purl.uniprot.org/citations/3019675 | http://purl.uniprot.org/core/pages | "1959-1966"xsd:string |