| http://purl.uniprot.org/citations/3020431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3020431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3020431 | http://www.w3.org/2000/01/rdf-schema#comment | "Gelsolin is representative of a class of actin-modulating proteins found in lower eukaryotes to mammals, which sever actin filaments. Gelsolin found in the cytoplasm of cells is functionally similar to a mammalian plasma protein of similar size, originally called ADF or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25-amino-acid residue extension on plasma gelsolin which appears to account for the difference in relative molecular mass (Mr) between the proteins as assessed by SDS-polyacrylamide gel electrophoresis (PAGE), 93,000 (93K) and 90K, respectively. Here we report the isolation of full-length human plasma gelsolin complementary DNA clones from a HepG2 library. The inferred amino-acid sequence reveals the presence of a signal peptide, a long tandem repeat that matches the actin-binding domains of gelsolin, a tetrapeptide present in actin and extended regions of identical sequence with rabbit macrophage gelsolin. Southern blot analysis indicates that a single gene in the haploid genome encodes both protein forms."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.org/dc/terms/identifier | "doi:10.1038/323455a0"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.org/dc/terms/identifier | "doi:10.1038/323455a0"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Kwiatkowski D.J."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Kwiatkowski D.J."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Orkin S.H."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Orkin S.H."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Yin H.L."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Yin H.L."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Colten H.R."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Colten H.R."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Mole J.E."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Mole J.E."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Stossel T.P."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/author | "Stossel T.P."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/pages | "455-458"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/pages | "455-458"xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/title | "Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain."xsd:string |
| http://purl.uniprot.org/citations/3020431 | http://purl.uniprot.org/core/title | "Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain."xsd:string |