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http://purl.uniprot.org/citations/30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/30219884http://www.w3.org/2000/01/rdf-schema#comment"Cesium (Cs+) is known to compete with the macronutrient potassium (K+) inside and outside of plants and to inhibit plant growth at high concentrations. However, the detailed molecular mechanisms of how Cs+ exerts its deleterious effects on K+ accumulation in plants are not fully elucidated. Here, we show that mutation in a member of the major K+ channel AKT1-KC1 complex renders Arabidopsis thaliana hypersensitive to Cs+. Higher severity of the phenotype and K+ loss were observed for these mutants in response to Cs+ than to K+ deficiency. Electrophysiological analysis demonstrated that Cs+, but not sodium, rubidium or ammonium, specifically inhibited K+ influx through the AKT1-KC1 complex. In contrast, Cs+ did not inhibit K+ efflux through the homomeric AKT1 channel that occurs in the absence of KC1, leading to a vast loss of K+. Our observation suggests that reduced K+ accumulation due to blockage/competition in AKT1 and other K+ transporters/channels by Cs+ plays a major role in plant growth retardation. This report describes the mechanical role of Cs+ in K+ accumulation, and in turn in plant performance, providing actual evidence at the plant level for what has long been believed, i.e. K+ channels are, therefore AKT1 is, 'blocked' by Cs+."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.org/dc/terms/identifier"doi:10.1093/pcp/pcy188"xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/author"Miyazaki T."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/author"Shin R."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/author"Saito S."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/author"Uozumi N."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/author"Adams E."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/name"Plant Cell Physiol"xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/pages"63-76"xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/title"Cesium Inhibits Plant Growth Primarily Through Reduction of Potassium Influx and Accumulation in Arabidopsis."xsd:string
http://purl.uniprot.org/citations/30219884http://purl.uniprot.org/core/volume"60"xsd:string
http://purl.uniprot.org/citations/30219884http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/30219884
http://purl.uniprot.org/citations/30219884http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/30219884
http://purl.uniprot.org/uniprot/#_F4JV33-mappedCitation-30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/#_F4JV35-mappedCitation-30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/#_A0A1P8B0E9-mappedCitation-30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/#_Q38998-mappedCitation-30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/#_P92960-mappedCitation-30219884http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/A0A1P8B0E9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/Q38998http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/F4JV33http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/P92960http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30219884
http://purl.uniprot.org/uniprot/F4JV35http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30219884