http://purl.uniprot.org/citations/3025083 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3025083 | http://www.w3.org/2000/01/rdf-schema#comment | "Recombinant mouse strains with crossovers in the I region of the H-2 major histocompatibility complex were examined by restriction fragment analysis for the presence of polymorphic restriction sites within the E beta and E alpha genes. Nine recombinant mouse strains were shown to have crossed over within a 5 kb DNA segment that contains the large intron between the second and third exons of the E beta gene. These results are in accord with previous studies mapping a recombination hot spot within this gene. Seven recombinant mouse strains between the p and k haplotypes were shown to have crossed over in a 6 kb segment within the E alpha gene. These results show the existence of a recombination hot spot within the E alpha gene. Comparison of the H-2 haplotypes involved in these two recombination hot spots suggests that a specific DNA sequence in b, s, f, and q haplotypes may act to promote recombination in the E beta gene and a specific DNA sequence in the p haplotype may act to promote recombination in the E alpha gene."xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00377952"xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/author | "Lafuse W.P."xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/author | "David C.S."xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/pages | "352-360"xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/title | "Recombination hot spots within the I region of the mouse H-2 complex map to the E beta and E alpha genes."xsd:string |
http://purl.uniprot.org/citations/3025083 | http://purl.uniprot.org/core/volume | "24"xsd:string |
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