| http://purl.uniprot.org/citations/30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30261904 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundThe mechanism by which c-Myc exerts its oncogenic functions is not completely clear and different hypotheses are still under investigation. The knowledge of the capacity of c-Myc to bind exclusively E-box sequences determined the discrepancy between, on the one hand, genomic studies showing the binding of c-Myc to all active promoters and, on the other hand, the evidence that only 60% or less of the binding sites have E-box sequences.Main bodyIn this review, we provide support to the hypothesis that the cooperation of c-Myc with transcriptional cofactors mediates c-Myc-induced cellular functions. We produce evidence that recently identified cofactors are involved in c-Myc control of survival mechanisms of cancer cells.ConclusionThe identification of new c-Myc cofactors could favor the development of therapeutic strategies able to compensate the difficulty of targeting c-Myc."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.org/dc/terms/identifier | "doi:10.1186/s13046-018-0912-2"xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Fanciulli M."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Locatelli F."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Folgiero V."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Iacovelli S."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Sorino C."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/author | "Caforio M."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/name | "J Exp Clin Cancer Res"xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/pages | "239"xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/title | "Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis."xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/30261904 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30261904 |
| http://purl.uniprot.org/citations/30261904 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30261904 |
| http://purl.uniprot.org/uniprot/#_A0A0B4J1R1-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_A0N2G3-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_A0A224B085-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJ86-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJ87-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJ88-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJB2-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJB3-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |
| http://purl.uniprot.org/uniprot/#_B3CJB8-mappedCitation-30261904 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30261904 |