| http://purl.uniprot.org/citations/30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30313118 | http://www.w3.org/2000/01/rdf-schema#comment | "Psoriasis vulgaris (PsV), also known as plaque psoriasis, is a life-threatening autoimmune skin disease. Inflammatory factors may contribute to the development of PsV. Present study aimed to explore the association of endoplasmic reticulum aminopeptidase 1 (ERAP1) gene polymorphisms (rs26653 and rs27524) with PsV susceptibility in a Chinese Han population. Subgroup analysis was also performed based on the onset of PsV.Present case-control study included 143 patients with PsV and 149 healthy controls. Direct sequencing method was used for genotyping ERAP1 polymorphisms. Chi-squared test was used to estimate the association between ERAP1 polymorphisms and PsV susceptibility. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess association strength.The polymorphism rs26653 was positively correlated with PsV susceptibility (CC vs GG, P = .047, OR = 1.964, 95% CI = 1.006-3.834; C vs G, P = .042, OR = 1.403, 95% CI = 1.011-1.946). Meanwhile, its CC genotype and C allele were positively associated with the early onset of PsV (P = .036, OR = 2.080, 95% CI = 1.044-4.145; P = .034, OR = 1.443, 95% CI = 1.028-2.024) and increased PsV risk in the subgroup with family history (P = .029, OR = 2.149, 95% CI = 1.075-4.296; P = .027, OR = 1.466, 95% CI = 1.044-2.059).ERAP1 gene rs26653 polymorphism may increase the risk of PsV in Chinese Han population."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.org/dc/terms/identifier | "doi:10.1097/md.0000000000012828"xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Chen Y."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Fu Y."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Liu R."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Wang R."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/author | "Bai N."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/name | "Medicine (Baltimore)"xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/pages | "e12828"xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/title | "Association of ERAP1 gene polymorphisms with the susceptibility to psoriasis vulgaris: A case-control study."xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://purl.uniprot.org/core/volume | "97"xsd:string |
| http://purl.uniprot.org/citations/30313118 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30313118 |
| http://purl.uniprot.org/citations/30313118 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A0P0LIR5-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A075BSP6-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A075BTL2-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A075BV59-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A075BW43-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A0A7E6D4-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A0A7E6D8-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A0A7E6I2-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |
| http://purl.uniprot.org/uniprot/#_A0A0A7E6J5-mappedCitation-30313118 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30313118 |