| http://purl.uniprot.org/citations/30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30315165 | http://www.w3.org/2000/01/rdf-schema#comment | "Circadian rhythms are orchestrated by a master clock that emerges from a network of circadian pacemaker neurons. The master clock is synchronized to external light/dark cycles through photoentrainment, but the circuit mechanisms underlying visual photoentrainment remain largely unknown. Here, we report that Drosophila has eye-mediated photoentrainment via a parallel pacemaker neuron organization. Patch-clamp recordings of central circadian pacemaker neurons reveal that light excites most of them independently of one another. We also show that light-responding pacemaker neurons send their dendrites to a neuropil called accessary medulla (aMe), where they make monosynaptic connections with Hofbauer-Buchner eyelet photoreceptors and interneurons that transmit compound-eye signals. Laser ablation of aMe and eye removal both abolish light responses of circadian pacemaker neurons, revealing aMe as a hub to channel eye inputs to central circadian clock. Taken together, we demonstrate that the central clock receives eye inputs via hub-organized parallel circuits in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-018-06506-5"xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Yang T."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Tang M."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Deng B."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Xiao N."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Yoshii T."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Cao L.H."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Li M.T."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/author | "Luo D.G."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/pages | "4247"xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/title | "Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/30315165 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30315165 |
| http://purl.uniprot.org/citations/30315165 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30315165 |
| http://purl.uniprot.org/uniprot/#_A0A6F7SN88-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_E1JJD5-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_O01668-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_O96690-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_P13217-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_M9PFL5-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |
| http://purl.uniprot.org/uniprot/#_Q24106-mappedCitation-30315165 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30315165 |