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http://purl.uniprot.org/citations/30332655http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/30332655http://www.w3.org/2000/01/rdf-schema#comment"Paxillin is a scaffold protein that participates in focal adhesion signaling in mammalian cells. Fission yeast paxillin ortholog, Pxl1, is required for contractile actomyosin ring (CAR) integrity and collaborates with the β-glucan synthase Bgs1 in septum formation. We show here that Pxl1's main function is to recruit calcineurin (CN) phosphatase to the actomyosin ring; and thus the absence of either Pxl1 or calcineurin causes similar cytokinesis defects. In turn, CN participates in the dephosphorylation of the Cdc15 F-BAR protein, which recruits and concentrates Pxl1 at the CAR. Our findings suggest the existence of a positive feedback loop between Pxl1 and CN and establish that Pxl1 is a crucial component of the CN signaling pathway during cytokinesis."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.org/dc/terms/identifier"doi:10.1016/j.celrep.2018.09.062"xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Perez P."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Ribas J.C."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Pinar M."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Correa-Bordes J."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Coll P.M."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Martin-Garcia R."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Rincon S.A."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Viana R.A."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/author"Arribas V."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/name"Cell Rep"xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/pages"772-783.e4"xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/title"Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast."xsd:string
http://purl.uniprot.org/citations/30332655http://purl.uniprot.org/core/volume"25"xsd:string
http://purl.uniprot.org/citations/30332655http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/30332655
http://purl.uniprot.org/citations/30332655http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/30332655
http://purl.uniprot.org/uniprot/Q12705#attribution-690E9C4426C2FD5E615A6C20FA86A5A1http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/30332655
http://purl.uniprot.org/uniprot/Q12705#attribution-8D73055A5507329AB89455C305C748F4http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/30332655
http://purl.uniprot.org/uniprot/Q12705#attribution-E7D87F1E45C557792D618CA3D7721FB0http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/30332655
http://purl.uniprot.org/uniprot/O74398#attribution-690E9C4426C2FD5E615A6C20FA86A5A1http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/30332655
http://purl.uniprot.org/uniprot/O74398#attribution-E7D87F1E45C557792D618CA3D7721FB0http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/30332655
http://purl.uniprot.org/uniprot/#_Q10287-mappedCitation-30332655http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30332655