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http://purl.uniprot.org/citations/3033633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3033633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3033633http://www.w3.org/2000/01/rdf-schema#comment"The broad-spectrum mercurial-resistance plasmid pDU1358 was analyzed by cloning the resistance determinants and preparing a physical and genetic map of a 45-kilobase (kb) region of the plasmid that contains two separate mercurial-resistance operons that mapped about 20 kb apart. One encoded narrow-spectrum mercurial resistance to Hg2+ and a few organomercurials; the other specified broad-spectrum resistance to phenylmercury and additional organomercurials. Each determinant governed mercurial transport functions. Southern DNA X DNA hybridization experiments using gene-specific probes from the plasmid R100 mer operon indicated close homology with the R100 determinant. The 2153 base pairs of the promoter-distal part of the broad-spectrum Hg2+-resistance operon of pDU1358 were sequenced. This region included the 3'-terminal part of the merA gene, merD, unidentified reading frame URF1, and a part of URF2 homologous to previously sequenced determinants of plasmid R100. Between the merA and merD genes, an open reading frame encoding a 212 amino acid polypeptide was identified as the merB gene that determines the enzyme organomercurial lyase that cleaves the C--Hg bond of phenylmercury."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.10.3112"xsd:string
http://purl.uniprot.org/citations/3033633http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.10.3112"xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Foster T.J."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Foster T.J."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Silver S."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Silver S."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Griffin H.G."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Griffin H.G."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Misra T.K."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/author"Misra T.K."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/pages"3112-3116"xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/pages"3112-3116"xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/title"Cloning and DNA sequence of the mercuric- and organomercurial-resistance determinants of plasmid pDU1358."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/title"Cloning and DNA sequence of the mercuric- and organomercurial-resistance determinants of plasmid pDU1358."xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3033633http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3033633http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3033633
http://purl.uniprot.org/citations/3033633http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3033633