| http://purl.uniprot.org/citations/3034582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3034582 | http://www.w3.org/2000/01/rdf-schema#comment | "The genetic diversity between the t12 and tw5 haplotype chromosomes was studied by analyzing the molecular organization of the H-2K region. Twenty-one cosmid clones spanning over 150 kb of the H-2K region of both t-haplotypes were defined, and high resolution restriction maps were determined. Detailed comparison of the t12 and tw5 restriction maps revealed the following. (i) The H-2K regions of both t-haplotypes retain a very similar molecular organization to that reported for B10, BALB/c and AKR. The nucleotide sequence diversity estimated from restriction site polymorphism is 0.68% between the t12 and tw5 haplotypes; these two t-haplotypes are no more similar to one another than BALB/c is to AKR. (ii) Genetic recombination is strongly implicated in generating H-2 polymorphism. (iii) Genetic polymorphisms, defined as small restriction fragment size differences, are observed at multiple sites along the H-2K region. An Alu-like B2 sequence and BAM5-R homologous sequence were identified as the inserted/deleted DNA segments of two of these sites, suggesting that insertion/deletion of mobile elements is a general mechanism for generating genetic diversity."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1987.tb04722.x"xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Abe K."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Park C.H."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Bennett D."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Shin H.S."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Artzt K."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/author | "Uehara H."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/pages | "83-90"xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/title | "The molecular organization of the H-2K region of two t-haplotypes: implications for the evolution of genetic diversity."xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/3034582 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3034582 |
| http://purl.uniprot.org/citations/3034582 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3034582 |
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| http://purl.uniprot.org/uniprot/#_A0A3Q4EGP3-mappedCitation-3034582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3034582 |
| http://purl.uniprot.org/uniprot/#_A0A482CGP7-mappedCitation-3034582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3034582 |
| http://purl.uniprot.org/uniprot/#_A0A494B9G2-mappedCitation-3034582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3034582 |
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