| http://purl.uniprot.org/citations/3036867 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3036867 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3036867 | http://www.w3.org/2000/01/rdf-schema#comment | "The human cell surface antigen 4F2 is a disulfide-linked heterodimer consisting of a glycosylated heavy chain and a nonglycosylated light chain. The antigen is ubiquitously expressed on proliferating cells but only in resting cells from certain tissues. Its function has been proposed to relate to cellular Ca2+/Na+ exchange. We describe the molecular cloning of the 4F2 heavy chain gene and cDNA by a gene transfer approach. Part of the gene was isolated from a genomic lambda library constructed with DNA of a secondary transfectant L cell line that expresses 4F2 antigen. A gene-specific probe derived from the phage inserts was used to isolate two full length cDNA clones. Both cDNA clones directed the expression of 4F2 antigen in transfected mouse L cells. The 4F2 antigen heavy chain gene specifies a 2.1-kilobase mRNA with an open reading frame coding for a 529-residue protein of 58 kDa. The protein lacks an NH2-terminal signal peptide but contains an internal transmembrane-spanning region and four potential glycosylation sites in its COOH-terminal domain. We predict that the 4F2 antigen heavy chain is a transmembrane protein with a cytoplasmic NH2 terminus of 81 amino acids. The antigen shows no homology to known protein sequences."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)47972-0"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)47972-0"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "Teixeira S."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "Teixeira S."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "Kuehn L.C."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "Kuehn L.C."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "di Grandi S."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/author | "di Grandi S."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/pages | "9574-9580"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/pages | "9574-9580"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/title | "Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/title | "Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus."xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/volume | "262"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://purl.uniprot.org/core/volume | "262"xsd:string |
| http://purl.uniprot.org/citations/3036867 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3036867 |
| http://purl.uniprot.org/citations/3036867 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3036867 |
| http://purl.uniprot.org/citations/3036867 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3036867 |
| http://purl.uniprot.org/citations/3036867 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3036867 |