| http://purl.uniprot.org/citations/3039496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3039496 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3039496 | http://www.w3.org/2000/01/rdf-schema#comment | "Renin (EC 3.4.23.15) is an aspartyl protease that cleaves its only known substrate, angiotensinogen, to release the vasopressor hormone angiotensin. We have isolated full-length cDNAs for renin from a rat kidney cDNA library. The cDNAs are complementary to a 1434-nucleotide rat kidney mRNA that encodes preprorenin, the 402-amino acid precursor of renin. This rat cDNA was used to isolate the complete copy of a renin gene from a rat genomic library, and a comparison of this genomic clone with rat genomic DNA showed that renin is a single-copy gene in the rat. Rat renin is 85% identical to one mouse renin isozyme (renin-1) and 81% identical to the second mouse renin isozyme (renin-2), suggesting that the duplication of the mouse renin genes is a more recent event than the speciation of rats and mice. Analyses of rat, human, and mouse renin sequences revealed that the potential to form two-chain renin is apparently peculiar to mouse renin, and the expression of a tenth exon (which results in a three-amino acid insertion) is observed only in the human renin gene."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.84.16.5605"xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.84.16.5605"xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3039496 |
| http://purl.uniprot.org/citations/3039496 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3039496 |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Lynch K.R."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Lynch K.R."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Burnham C.E."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Burnham C.E."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Frank B.M."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Frank B.M."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Hawelu-Johnson C.L."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/author | "Hawelu-Johnson C.L."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/pages | "5605-5609"xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/pages | "5605-5609"xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/title | "Molecular cloning of rat renin cDNA and its gene."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/title | "Molecular cloning of rat renin cDNA and its gene."xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/volume | "84"xsd:string |
| http://purl.uniprot.org/citations/3039496 | http://purl.uniprot.org/core/volume | "84"xsd:string |