| http://purl.uniprot.org/citations/30460098 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30460098 | http://www.w3.org/2000/01/rdf-schema#comment | "To explore the function of VIG-1 in Caenorhabditis elegans, we analyzed the phenotypes of two vig-1 deletion mutants: vig-1(tm3383) and vig-1(ok2536). Both vig-1 mutants exhibited phenotypes associated with genome instability, such as a high incidence of males (Him) and increased embryonic lethality. These phenotypes became more evident in succeeding generations, implying that the germline of vig-1 accumulates DNA damage over generations. To examine whether vig-1 causes a defect in the DNA damage response, we treated worms with UV or camptothecin, a specific topoisomerase I inhibitor. We observed that the embryonic survival of the vig-1 mutants was reduced compared with that of the wild-type worms. Our results thus suggest that VIG-1 is required for maintaining genome stability in response to endogenous and exogenous genotoxic stresses."xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.org/dc/terms/identifier | "doi:10.1080/19768354.2018.1476410"xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/author | "Park Y.S."xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/author | "Cho N.J."xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/author | "Vasamsetti B.M.K."xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/name | "Anim Cells Syst (Seoul)"xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/pages | "197-204"xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/title | "VIG-1 is required for maintenance of genome stability in Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://purl.uniprot.org/core/volume | "22"xsd:string |
| http://purl.uniprot.org/citations/30460098 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30460098 |
| http://purl.uniprot.org/citations/30460098 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30460098 |
| http://purl.uniprot.org/uniprot/#_H2KYR1-mappedCitation-30460098 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30460098 |
| http://purl.uniprot.org/uniprot/H2KYR1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30460098 |