| http://purl.uniprot.org/citations/30518761 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30518761 | http://www.w3.org/2000/01/rdf-schema#comment | "Detection of conserved microbial patterns by host cell surface pattern recognition receptors (PRRs) activates innate immunity. The FLAGELLIN-SENSITIVE 2 (FLS2) receptor perceives bacterial flagellin and recruits another PRR, BAK1 and the cytoplasmic-kinase BIK1 to form an active co-receptor complex that initiates antibacterial immunity in Arabidopsis. Molecular mechanisms that transmit flagellin perception from the plasma-membrane FLS2-associated receptor complex to intracellular events are less well understood. Here, we show that flagellin induces the conjugation of the SMALL UBIQUITIN-LIKE MODIFIER (SUMO) protein to FLS2 to trigger release of BIK1. Disruption of FLS2 SUMOylation can abolish immune responses, resulting in susceptibility to bacterial pathogens in Arabidopsis. We also identify the molecular machinery that regulates FLS2 SUMOylation and demonstrate a role for the deSUMOylating enzyme, Desi3a in innate immunity. Flagellin induces the degradation of Desi3a and enhances FLS2 SUMOylation to promote BIK1 dissociation and trigger intracellular immune signalling."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-018-07696-8"xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Lee J."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Srivastava M."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Zhang C."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Sadanandom A."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Verma V."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Bennett M.J."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Srivastava A.K."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Orosa B."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Fernandes A."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Campanaro A."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "Yates G."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/author | "De Vega D."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/pages | "5185"xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/title | "SUMO conjugation to the pattern recognition receptor FLS2 triggers intracellular signalling in plant innate immunity."xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/30518761 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30518761 |
| http://purl.uniprot.org/citations/30518761 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30518761 |
| http://purl.uniprot.org/uniprot/#_A0A178V333-mappedCitation-30518761 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30518761 |
| http://purl.uniprot.org/uniprot/#_C0LGU8-mappedCitation-30518761 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30518761 |
| http://purl.uniprot.org/uniprot/#_F4JIX9-mappedCitation-30518761 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30518761 |