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http://purl.uniprot.org/citations/30556142http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/30556142http://www.w3.org/2000/01/rdf-schema#comment"Organ size in plants is controlled by the interaction between genotype and the environment. Seed size, an important agronomic trait, largely determines yield and is an important focus of research. However, the genetic components underpinning natural variation of seed size in undomesticated species remain largely unidentified. Here we report a genome-wide association study (GWAS) of seed size in Arabidopsis thaliana, which identified 38 significantly associated loci, including one locus associated with CYCB1;4. Natural variations in CYCB1;4, which encodes a cyclin protein involved in the cell cycle, significantly influence seed size in A. thaliana. Transgenic plants with enhanced CYCB1;4 expression show normal development, exhibit increased seed size as a result of an accelerated cell cycle progression, and tend to produce higher yields. By contrast, cycb1;4 mutants have smaller seeds, and the effect is especially pronounced in a large-seed accession. The temporal and spatial expression pattern of CYCB1;4 suggests that this gene may function in both maternal tissues and zygotic tissues to coordinate the final size of seeds. Taken together, our results provide genetic insights into natural variation in seed size in Arabidopsis. Moreover, CYCB1;4 homologs in other crops could have great potential as targets for efforts aimed at yield improvement."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.org/dc/terms/identifier"doi:10.1111/nph.15642"xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"Deng X.W."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"Wang X."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"Yang L."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"Yang M."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"He G."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/author"Ren D."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/name"New Phytol"xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/pages"895-906"xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/title"A new regulator of seed size control in Arabidopsis identified by a genome-wide association study."xsd:string
http://purl.uniprot.org/citations/30556142http://purl.uniprot.org/core/volume"222"xsd:string
http://purl.uniprot.org/citations/30556142http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/30556142
http://purl.uniprot.org/citations/30556142http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/30556142
http://purl.uniprot.org/uniprot/#_A0A178VPU5-mappedCitation-30556142http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30556142
http://purl.uniprot.org/uniprot/#_O48790-mappedCitation-30556142http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30556142
http://purl.uniprot.org/uniprot/A0A178VPU5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30556142
http://purl.uniprot.org/uniprot/O48790http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30556142