http://purl.uniprot.org/citations/30566253 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/30566253 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundAdipokines have been suggested to play an important role in the pathogenesis of polycystic ovarian syndrome (PCOS). Omentin is an adipokine secreted essentially by visceral adipose tissue with an insulin-sensitizing effect. Insulin resistance (IR) is a common feature of PCOS, therefore the aim of this study was to investigate omentin-1 level in adolescent girls with PCOS and its relationship with IR and androgens.MethodA total of 41 obese girls with PCOS, and 30 age- and body mass index (BMI)-matched obese girls without PCOS were enrolled in the study. The demographic, clinic and laboratory characteristics of the groups were compared. Additionally, bivariate correlation analysis of omentin-1 with BMI standard deviation score (BMI-SDS), insulin, glucose, homeostatic model assessment of IR (HOMA-IR), total and free testosterone was performed.ResultsIn the PCOS group HOMA-IR, free and total testosterone were higher than in the control group. Omentin-1 was lower in the PCOS group compared with the controls (55.01 ± 7.99 ng/mL vs 59.10 ± 7.02 ng/mL, respectively; P = 0.027). Omentin-1 was inversely correlated with free testosterone (r = -0.527, P = 0.030) and BMI-SDS (r = -0.241, P = 0.046) but it was not correlated with total testosterone, HOMA-IR, glucose, insulin or serum lipids.ConclusionOmentin-1 was lower in obese girls with PCOS and hyperandrogenism was associated with this condition."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.org/dc/terms/identifier | "doi:10.1111/ped.13761"xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Ozgen I.T."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Selek S."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Cesur Y."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Guzel G."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Kutlu E."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/author | "Oruclu S."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/name | "Pediatr Int"xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/pages | "147-151"xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/title | "Omentin-1 level in adolescents with polycystic ovarian syndrome."xsd:string |
http://purl.uniprot.org/citations/30566253 | http://purl.uniprot.org/core/volume | "61"xsd:string |
http://purl.uniprot.org/citations/30566253 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30566253 |
http://purl.uniprot.org/citations/30566253 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30566253 |
http://purl.uniprot.org/uniprot/#_Q5IWS5-mappedCitation-30566253 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30566253 |
http://purl.uniprot.org/uniprot/#_Q8WWA0-mappedCitation-30566253 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30566253 |
http://purl.uniprot.org/uniprot/Q8WWA0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30566253 |
http://purl.uniprot.org/uniprot/Q5IWS5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30566253 |