| http://purl.uniprot.org/citations/3056912 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3056912 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3056912 | http://www.w3.org/2000/01/rdf-schema#comment | "In bacteria, the complex nucleoid structure is folded and maintained by negative superhelical tension and a set of type II DNA-binding proteins, also called histonelike proteins. The most abundant type II DNA-binding protein is HU. Southern blot analysis showed that Salmonella typhimurium contained two HU genes that corresponded to Escherichia coli genes hupA (encoding HU-2 protein) and hupB (encoding HU-1). Salmonella hupA was cloned, and the nucleotide sequence of the gene was determined. Comparison of hupA of E. coli and S. typhimurium revealed that the HU-2 proteins were identical and that there was high conservation of nucleotide sequences outside the coding frames of the genes. A 300-member genomic library of S. typhimurium was constructed by using random transposition of MudP, a specialized chimeric P22-Mu phage that packages chromosomal DNA unidirectionally from its insertion point. Oligonucleotide hybridization against the library identified one MudP insertion that lies within 28 kilobases of hupA; the MudP was 12% linked to purH at 90.5 min on the standard map. Plasmids expressing HU-2 had a surprising phenotype; they caused growth arrest when they were introduced into E. coli strains bearing a himA or hip mutation. These results suggest that IHF and HU have interactive roles in bacteria."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.170.12.5751-5758.1988"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.170.12.5751-5758.1988"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/author | "Higgins N.P."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/author | "Higgins N.P."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/author | "Hillyard D."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/author | "Hillyard D."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/pages | "5751-5758"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/pages | "5751-5758"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/title | "Primary structure and mapping of the hupA gene of Salmonella typhimurium."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/title | "Primary structure and mapping of the hupA gene of Salmonella typhimurium."xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/volume | "170"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://purl.uniprot.org/core/volume | "170"xsd:string |
| http://purl.uniprot.org/citations/3056912 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3056912 |
| http://purl.uniprot.org/citations/3056912 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3056912 |
| http://purl.uniprot.org/citations/3056912 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3056912 |
| http://purl.uniprot.org/citations/3056912 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3056912 |
| http://purl.uniprot.org/uniprot/P0A1R6 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/3056912 |
| http://purl.uniprot.org/uniprot/#_P0A1R6-citation-3056912 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/3056912 |