| http://purl.uniprot.org/citations/30595383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30595383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30595383 | http://www.w3.org/2000/01/rdf-schema#comment | "CDC-48 is a AAA (ATPases associated with diverse cellular activities) chaperone and participates in a wide range of cellular activities. Its functional diversity is determined by differential binding of a variety of cofactors. In this study, we analyzed the physiological role of a CDC-48 cofactor UBXN-6 in Caenorhabditis elegans. The amount of UBXN-6 was markedly increased upon starvation, but not with the treatment of tunicamycin and rapamycin. The induction upon starvation is a unique characteristic for UBXN-6 among C-terminal cofactors of CDC-48. During starvation, lysosomal activity is triggered for rapid clearance of cellular materials. We observed the lysosomal activity by monitoring GLO-1::GFP, a marker for lysosome-related organelles. We found that more puncta of GLO-1::GFP were observed in the ubxn-6 deletion mutant after 12 h starvation compared with the wild-type strain. Taken together, we propose that UBXN-6 is involved in clearance of cellular materials upon starvation in C. elegans."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2018.12.155"xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2018.12.155"xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Murayama Y."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Murayama Y."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Yamanaka K."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Yamanaka K."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Ogura T."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Ogura T."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Mojumder S."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Mojumder S."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Sawamura R."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/author | "Sawamura R."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/pages | "462-468"xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/pages | "462-468"xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/title | "Functional characterization of UBXN-6, a C-terminal cofactor of CDC-48, in C. elegans."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/title | "Functional characterization of UBXN-6, a C-terminal cofactor of CDC-48, in C. elegans."xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/volume | "509"xsd:string |
| http://purl.uniprot.org/citations/30595383 | http://purl.uniprot.org/core/volume | "509"xsd:string |