| http://purl.uniprot.org/citations/30628436 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30628436 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30628436 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/30628436 | http://www.w3.org/2000/01/rdf-schema#comment | "Mycofactocin is a putative redox cofactor and is classified as a ribosomally synthesized and post-translationally modified peptide (RiPP). Some RiPP natural products, including mycofactocin, rely on a radical S-adenosylmethionine (RS, SAM) protein to modify the precursor peptide. Mycofactocin maturase, MftC, is a unique RS protein that catalyzes the oxidative decarboxylation and C-C bond formation on the precursor peptide MftA. However, the number, chemical nature, and catalytic roles for the MftC [Fe-S] clusters remain unknown. Here, we report that MftC binds a RS [4Fe-4S] cluster and two auxiliary [4Fe-4S] clusters that are required for MftA modification. Furthermore, electron paramagnetic resonance spectra of MftC suggest that SAM and MftA affect the environments of the RS and Aux I cluster, whereas the Aux II cluster is unaffected by the substrates. Lastly, reduction potential assignments of individual [4Fe-4S] clusters by protein film voltammetry show that their potentials are within 100 mV of each other."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.org/dc/terms/identifier | "doi:10.1021/acs.biochem.8b01082"xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.org/dc/terms/identifier | "doi:10.1021/acs.biochem.8b01082"xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Pandelia M.E."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Pandelia M.E."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Elliott S.J."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Elliott S.J."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Walker L.M."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Walker L.M."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Latham J.A."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Latham J.A."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Ayikpoe R."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Ayikpoe R."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Bonitatibus S."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Bonitatibus S."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Eaton G.R."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Eaton G.R."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Eaton S.S."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Eaton S.S."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Langton M."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Langton M."xsd:string |
| http://purl.uniprot.org/citations/30628436 | http://purl.uniprot.org/core/author | "Ngendahimana T."xsd:string |