| http://purl.uniprot.org/citations/30664260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30664260 | http://www.w3.org/2000/01/rdf-schema#comment | "Psoriasis is a chronic inflammatory disease, and microRNAs have been reported to regulate the pathogenesis of psoriasis. Up-regulated miR-744-3p level was identified to associate with psoriasis while the precise functions of miR-744-3p in psoriasis were not well-elucidated. We first confirmed the up-regulation of miR-744-3p in psoriasis by measuring its expression level in psoriatic samples. We explored the roles of miR-744-3p on keratinocytes proliferation and differentiation. We searched the targets of miR-744-3p and evaluated the roles of one target, KLLN on keratinocytes proliferation and differentiation. We confirmed the up-regulation of miR-744-3p in psoriatic samples. MiR-744-3p promoted keratinocytes proliferation while inhibited differentiation. MiR-744-3p targeted KLLN and overexpression of miR-744-3p resulted in decreased expression of KLLN. Overexpression of KLLN prevented the effects of miR-744-3p on keratinocytes proliferation and differentiation. MiR-744-3p regulated the proliferation and differentiation of keratinocytes through targeting KLLN in psoriasis."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.org/dc/terms/identifier | "doi:10.1111/exd.13888"xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Li L."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Wang C."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Du W."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/author | "Zong J."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/name | "Exp Dermatol"xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/pages | "283-291"xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/title | "MiR-744-3p regulates keratinocyte proliferation and differentiation via targeting KLLN in psoriasis."xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/30664260 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30664260 |
| http://purl.uniprot.org/citations/30664260 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30664260 |
| http://purl.uniprot.org/uniprot/#_B2CW77-mappedCitation-30664260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30664260 |
| http://purl.uniprot.org/uniprot/B2CW77 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30664260 |