| http://purl.uniprot.org/citations/30675064 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30675064 | http://www.w3.org/2000/01/rdf-schema#comment | "There is a growing appreciation for the importance of the gut microbiota as a therapeutic target in various diseases. However, there are only a handful of known commensal strains that can potentially be used to manipulate host physiological functions. Here we isolate a consortium of 11 bacterial strains from healthy human donor faeces that is capable of robustly inducing interferon-γ-producing CD8 T cells in the intestine. These 11 strains act together to mediate the induction without causing inflammation in a manner that is dependent on CD103+ dendritic cells and major histocompatibility (MHC) class Ia molecules. Colonization of mice with the 11-strain mixture enhances both host resistance against Listeria monocytogenes infection and the therapeutic efficacy of immune checkpoint inhibitors in syngeneic tumour models. The 11 strains primarily represent rare, low-abundance components of the human microbiome, and thus have great potential as broadly effective biotherapeutics."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41586-019-0878-z"xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Hattori M."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Inoue T."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Vlamakis H."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Xavier R.J."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Norman J.M."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Tanoue T."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Shiota A."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Kaisho T."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Morita S."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Kawakami Y."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Honda K."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Suda W."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Sugiura Y."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Yaguchi T."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Suematsu M."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Takeshita K."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Sugita K."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Roberts B."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Riethmacher D."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Plichta D.R."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Atarashi K."xsd:string |
| http://purl.uniprot.org/citations/30675064 | http://purl.uniprot.org/core/author | "Narushima S."xsd:string |