| http://purl.uniprot.org/citations/30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30733440 | http://www.w3.org/2000/01/rdf-schema#comment | "Nervous systems exhibit myriad cell types, but understanding how this diversity arises is hampered by the difficulty to visualize and genetically-probe specific lineages, especially at early developmental stages prior to expression of unique molecular markers. Here, we use a genetic immortalization method to analyze the development of sensory neuron lineages in the Drosophila olfactory system, from their origin to terminal differentiation. We apply this approach to define a fate map of nearly all olfactory lineages and refine the model of temporal patterns of lineage divisions. Taking advantage of a selective marker for the lineage that gives rise to Or67d pheromone-sensing neurons and a genome-wide transcription factor RNAi screen, we identify the spatial and temporal requirements for Pointed, an ETS family member, in this developmental pathway. Transcriptomic analysis of wild-type and Pointed-depleted olfactory tissue reveals a universal requirement for this factor as a switch-like determinant of fates in these sensory lineages."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-019-08345-4"xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/author | "Benton R."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/author | "Cruchet S."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/author | "Chai P.C."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/author | "Wigger L."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/pages | "643"xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/title | "Sensory neuron lineage mapping and manipulation in the Drosophila olfactory system."xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/30733440 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30733440 |
| http://purl.uniprot.org/citations/30733440 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFQ2-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHS6-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHS7-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHV1-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEU2-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEZ1-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KHZ0-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KI43-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LEG2-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LF06-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LF15-mappedCitation-30733440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30733440 |