| http://purl.uniprot.org/citations/30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30786682 | http://www.w3.org/2000/01/rdf-schema#comment | "We have investigated the distribution of chemokine receptor 4 (CXCR4) and CD8-positive, tumour-infiltrating T lymphocytes (CD8+ TILs) in breast cancer subtypes and explored the relationship between them and the well-established conventional prognostic markers, including axillary lymph node involvement. A total of 250 breast cancer patients were included in the study. The patients were separated into luminal A+B, HER2 enriched/overexpressed (HER2+), and triple-negative, on the basis of their staining characteristics, via conventional staining methods. Immunohistochemical (IHC) staining for CXCR4 and CD8+ TILs were performed on the archival tissues from each patient. With increasing intensity of CXCR4 staining, there was a higher incidence of lymph node metastasis (p < 0.01). Similarly, there was a positive correlation between the primary tumour size, HER2+ subtype, lymphovascular invasion, and axillary lymph node involvement. Dense lymphocytic infiltration was observed in HER2+ and triple-negative patients. No correlation between CD8+ TILs in all sites and breast cancer subtypes was discovered. A reverse correlation was discovered with CD8+ TILs stained only intratumorally and CXCR4 expression. In conclusion, lymph node involvement correlates with higher CXCR4 expression in all breast cancer subtypes. Conversely, no such correlation is found with CD8+ TILs."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.org/dc/terms/identifier | "doi:10.5114/pjp.2018.81692"xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/author | "Kececi S.D."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/author | "Dag F."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/author | "Pehlivan F.S."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/author | "Sanal S.M."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/author | "Sivrikoz O.N."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/name | "Pol J Pathol"xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/pages | "335-341"xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/title | "Distribution of CXCR4 and tumour-infiltrating lymphocytes in breast cancer subtypes; their relationship with each other, axillary lymph node involvement, and other prognostic indicators."xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://purl.uniprot.org/core/volume | "69"xsd:string |
| http://purl.uniprot.org/citations/30786682 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30786682 |
| http://purl.uniprot.org/citations/30786682 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30786682 |
| http://purl.uniprot.org/uniprot/#_A0A0U3FJG0-mappedCitation-30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/#_A0A0U3GXA9-mappedCitation-30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/#_A0A8Q3WLL1-mappedCitation-30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/#_P61073-mappedCitation-30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/#_Q5MIL4-mappedCitation-30786682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/A0A8Q3WLL1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/Q5MIL4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/A0A0U3GXA9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/P61073 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30786682 |
| http://purl.uniprot.org/uniprot/A0A0U3FJG0 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30786682 |