| http://purl.uniprot.org/citations/30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30837153 | http://www.w3.org/2000/01/rdf-schema#comment | "Drosophila Trf4-1 (DmTrf4-1) is a polyadenylation polymerase or terminal nucleotidyl transferase (PAP/TENT) that has been reported to add poly(A) tails to snRNAs in nucleus or mRNAs in cytoplasm. Here, we found that the loss of Trf4-1 resulted in the reduction of mRNAs and primary miRNAs (pri-miRNAs) in both Drosophila S2 cells and adult flies. Interestingly, the role of Trf4-1 in transcription is independent of its PAP/TENT activity. Moreover, using the chromatin immunoprecipitation assay, we uncovered that the loss of Trf4-1 led to abnormal RNA polymerase II accumulation and reduced H3K4me3 binding in promoter regions. Thus, our study indicates a positive role of Trf4-1 in the transcription of mRNAs and pri-miRNAs."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2019.02.129"xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Fang Y."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Qiu Y."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Liu Y.'"xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Wang M."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Zhou X."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Yu Y."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/author | "Quan J."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/pages | "806-812"xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/title | "Drosophila Trf4-1 involves in mRNA and primary miRNA transcription."xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://purl.uniprot.org/core/volume | "511"xsd:string |
| http://purl.uniprot.org/citations/30837153 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30837153 |
| http://purl.uniprot.org/citations/30837153 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30837153 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFU8-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |
| http://purl.uniprot.org/uniprot/#_A0A126GUN5-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |
| http://purl.uniprot.org/uniprot/#_A4V1B2-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |
| http://purl.uniprot.org/uniprot/#_A1Z6M0-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |
| http://purl.uniprot.org/uniprot/#_E2QCS8-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |
| http://purl.uniprot.org/uniprot/#_P02299-mappedCitation-30837153 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30837153 |