| http://purl.uniprot.org/citations/30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30877185 | http://www.w3.org/2000/01/rdf-schema#comment | "Accumulating evidence suggests that miRNAs play a crucial role in the development of prostate cancer (PC); however, the role of miR-500 in PC remains poorly understood. The data presented here reveal abnormal increases in miR-500 expression in PC tissues and cell lines. Suppression of miR-500 expression significantly inhibited the proliferation of PC-3 and LnCap cells and was negatively regulative with low-density lipoprotein receptor-related protein 1B (LRP1B). Increased cell cycle arrest at the G1 stage and decreased protein expression of cyclinD1 and CDK2 was observed in response to miR-500 knockdown in PC-3 and LnCap cells, in combination with LRP1B overexpression. LRP1B was identified as a target of miR-500 and was significantly decreased in PC tissues. Taken together, these findings demonstrate that miR-500 plays an important role in the proliferation of PC cells via the inhibition of LRP1B expression."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.org/dc/terms/identifier | "doi:10.1042/bsr20181854"xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/author | "Cui R."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/name | "Biosci Rep"xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/pages | "BSR20181854"xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/title | "miR-500 promotes cell proliferation by directly targetting LRP1B in prostate cancer."xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://purl.uniprot.org/core/volume | "39"xsd:string |
| http://purl.uniprot.org/citations/30877185 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30877185 |
| http://purl.uniprot.org/citations/30877185 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30877185 |
| http://purl.uniprot.org/uniprot/#_Q4ZFV5-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q4ZG53-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53RA0-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53RG4-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53RL0-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53S26-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53S73-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53S76-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q53TB8-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_L8ECI0-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |
| http://purl.uniprot.org/uniprot/#_Q580W7-mappedCitation-30877185 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30877185 |