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http://purl.uniprot.org/citations/30951668http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/30951668http://www.w3.org/2000/01/rdf-schema#comment"Long-range (>10 μm) transport of electrons along networks of Geobacter sulfurreducens protein filaments, known as microbial nanowires, has been invoked to explain a wide range of globally important redox phenomena. These nanowires were previously thought to be type IV pili composed of PilA protein. Here, we report a 3.7 Å resolution cryoelectron microscopy structure, which surprisingly reveals that, rather than PilA, G. sulfurreducens nanowires are assembled by micrometer-long polymerization of the hexaheme cytochrome OmcS, with hemes packed within ∼3.5-6 Å of each other. The inter-subunit interfaces show unique structural elements such as inter-subunit parallel-stacked hemes and axial coordination of heme by histidines from neighboring subunits. Wild-type OmcS filaments show 100-fold greater conductivity than other filaments from a ΔomcS strain, highlighting the importance of OmcS to conductivity in these nanowires. This structure explains the remarkable capacity of soil bacteria to transport electrons to remote electron acceptors for respiration and energy sharing."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2019.03.029"xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Egelman E.H."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Gu Y."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Shen C."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Wang F."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Vu D."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Malvankar N.S."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Hochbaum A.I."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Srikanth V."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Yalcin S.E."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Yi S.M."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"O'Brien J.P."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/author"Ing N.L."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/pages"361-369.e10"xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/title"Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers."xsd:string
http://purl.uniprot.org/citations/30951668http://purl.uniprot.org/core/volume"177"xsd:string
http://purl.uniprot.org/citations/30951668http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/30951668
http://purl.uniprot.org/citations/30951668http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/30951668
http://purl.uniprot.org/uniprot/#_Q74A86-mappedCitation-30951668http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/30951668
http://purl.uniprot.org/uniprot/Q74A86http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/30951668