| http://purl.uniprot.org/citations/30954221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30954221 | http://www.w3.org/2000/01/rdf-schema#comment | "Circular RNAs (circRNAs) have recently been considered as key regulators in carcinogenesis. Nevertheless, the study of circRNAs involved in non-small cell lung cancer (NSCLC) remains largely unclear. In this study, we aim to explore the clinical significance, regulatory effect and mechanism of circ-FOXM1 in NSCLC. The results indicated that circ-FOXM1 overexpression was observed in NSCLC tissues and closely associated with lymph node invasion, higher TNM stage, and unfavorable prognosis. Furthermore, knockdown and ectopic expression of circ-FOXM1 significantly inhibited and promoted the growth, migration and invasion of NSCLC cells, respectively. Mechanistically, miR-1304-5p was discovered as a direct target of circ-FOXM1. Circ-FOXM1 upregulated the level of pancreatic progenitor cell differentiation and proliferation factor (PPDPF) and metastasis-associated in colon cancer 1 (MACC1) by sponging miR-1304-5p, thereby increasing the proliferation and invasion of NSCLC cells. Taken together, this work revealed that circ-FOXM1/miR-1304-5p/PPDPF/MACC1 signaling was essential for the development and progression of NSCLC."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2019.03.213"xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Liu G."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Shi H."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Wen X."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Zheng H."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Deng L."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Kong W."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/author | "Bi H."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/pages | "207-212"xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/title | "Circular RNA circ-FOXM1 facilitates cell progression as ceRNA to target PPDPF and MACC1 by sponging miR-1304-5p in non-small cell lung cancer."xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://purl.uniprot.org/core/volume | "513"xsd:string |
| http://purl.uniprot.org/citations/30954221 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/30954221 |
| http://purl.uniprot.org/citations/30954221 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/30954221 |
| http://purl.uniprot.org/uniprot/#_Q6ZN28-mappedCitation-30954221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30954221 |
| http://purl.uniprot.org/uniprot/#_Q9H3Y8-mappedCitation-30954221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/30954221 |
| http://purl.uniprot.org/uniprot/Q9H3Y8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30954221 |
| http://purl.uniprot.org/uniprot/Q6ZN28 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/30954221 |