| http://purl.uniprot.org/citations/30954333 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30954333 | http://www.w3.org/2000/01/rdf-schema#comment | "Nuclear actin has been implicated in a variety of DNA-related processes including chromatin remodeling, transcription, replication, and DNA repair. However, the mechanistic understanding of actin in these processes has been limited, largely due to a lack of research tools that address the roles of nuclear actin specifically, that is, distinct from its cytoplasmic functions. Recent findings support a model for homology-directed DNA double-strand break (DSB) repair in which a complex of ARP2 and ARP3 (actin-binding proteins 2 and 3) binds at the break and works with actin to promote DSB clustering and homology-directed repair. Further, it has been reported that relocalization of heterochromatic DSBs to the nuclear periphery in Drosophila is ARP2/3 dependent and actin-myosin driven. Here we provide an overview of the role of nuclear actin and actin-binding proteins in DNA repair, critically evaluating the experimental tools used and potential indirect effects."xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.tcb.2019.02.010"xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/author | "Shimada K."xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/author | "Gasser S.M."xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/author | "Hurst V."xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/name | "Trends Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/pages | "462-476"xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/title | "Nuclear Actin and Actin-Binding Proteins in DNA Repair."xsd:string |
| http://purl.uniprot.org/citations/30954333 | http://purl.uniprot.org/core/volume | "29"xsd:string |
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